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    Home » Low carb diets and the insulin lie, by Mukaila Kareem 
    Columnists

    Low carb diets and the insulin lie, by Mukaila Kareem 

    EditorBy EditorDecember 2, 2025No Comments4 Mins Read
    Dr Mukaila Kareem

    By Mukaila Kareem 

    For years, low carb advocates have claimed that lowering insulin requires cutting carbohydrates. This sounds convincing until you look at what insulin is and how fast it disappears from the bloodstream. The half-life of natural insulin is three to six minutes. Half-life simply means the time it takes for half of the hormone to be cleared from the bloodstream. Within minutes of blood glucose falling, most of the insulin is already gone. It is one of the fastest-clearing signals in human biology. This simple fact dismantles the claim that the body needs a special diet to bring insulin down.

    The clearest proof comes from the pharmaceutical industry. There are now nearly a dozen engineered insulin analogs on the market. Insulin analogs are man-made versions of the body’s native hormone with small structural changes that slow down or speed up how long they work. These analogs exist because human insulin vanishes too quickly to be useful as long-term therapy for diabetes. For example, long-acting basal insulin was invented because natural insulin lasts only a few minutes. Big Pharma stretched insulin’s lifespan artificially for patients who need extended coverage. This innovation only happened because the natural molecule is short lived. That truth sits in plain sight, and Big Pharma has capitalized on it for decades.

    Low carb crusaders sell their diet as the magic key for weight loss and for people with diabetes. They claim it works by lowering insulin, but this is not true. Again, insulin is degraded within minutes once blood glucose is lowered. Therefore, the diet does not lower insulin — biology does. The real issue is the nonstop flow of fuel in the modern world, not the presence of carbohydrates themselves.

    One of the strongest scientific arguments against the insulin myth comes from the Twin Cycle Hypothesis, which explains type 2 diabetes as the result of two overloaded organs: the liver and the pancreas. When the liver becomes stuffed with fat from chronic overnutrition, it releases excess glucose and fat into the bloodstream, forcing the pancreas to produce more insulin. Over time, fat also accumulates in the pancreas, slowing insulin release. But when metabolic overload is suddenly removed through severe calorie restriction, both organs recover quickly and insulin sensitivity returns with surprising speed.

    This rapid metabolic recovery is also seen after bariatric surgery and very-low-calorie diets. In both cases, insulin sensitivity improves within days, long before major weight loss occurs. The reason is simple. A sudden drop in nutrient flow relieves pressure on the liver and pancreas, allowing the body to clear insulin normally again. These clinical examples show that insulin is not the driver of disease. It is a fast-clearing signal responding to metabolic congestion.

    The real problem facing modern physiology is not stubborn insulin. It is stubborn substrate overload. Too much glucose arrives too often. Too much dietary fat enters a system that rarely engages its large muscles. Protein arrives all day long with no metabolic rest. The body reacts to this flood by pulsing insulin repeatedly, not because the hormone is misbehaving or long lasting, but because the environment is chaotic. Persistent high levels of blood insulin are a reflection of nutrient overload, not evidence of a hormone trapped in the bloodstream.

    Low carb ideology reverses the cause and effect. It suggests that high insulin is the driver of metabolic disease and therefore insulin must be lowered first by removing carbohydrates. Biology shows something different. The body clears insulin almost immediately when nutrient pressure drops. What remains elevated is the constant supply stream of food that modern life delivers. This nonstop input forces insulin to keep rising again and again. The problem is the river of nutrient substrate, not the hormone.

    People embraced the insulin explanation because it offered a single convenient culprit. It is easier to attack insulin than to address the frequency of eating, the absence of walking, the loss of physiological rhythm and the redox imbalance that builds from sedentary life. It is easier to market a diet than to teach mitochondrial congestion and explain thermodynamic overload. As a result, the conversation drifted away from physiology and settled into ideology.

    The human body does not need extreme diets to clear insulin. It needs time, space, and movement. A body that walks regularly and allows breaks between meals sees insulin return to its normal rhythm. The hormone rises when fuel arrives and falls when fuel stops arriving. Here is the simple truth: insulin is a rapid messenger responding to the environment, not a runaway hormone creating the problem. It does not drive obesity or type 2 diabetes. It simply responds to the nutrients that arrive, and lowering it requires no special diet, only less metabolic overload. Stop the insulin lie.

    Editor
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